TY - JOUR
T1 - Immune Benefits of Psychosocial Intervention for Atopic Dermatitis in Hong Kong Children
AU - Chan, Celia Hoi Yan
AU - Yin, Margaret Xi Can
AU - Guo, Dan Yuan
AU - Fung, Yat Lui
AU - Hon, Kam Lun Ellis
AU - Kung, Charmaine Jeng Sum
AU - Hui, Victoria Ka Ying
AU - Luk, David Chi Kong
AU - Cheng, James Wesley Ching Hei
AU - Chu, Ashleigh Ka Ying
AU - Tsang, Michelle Yuk Ping
AU - Lam, Sam Ying Yin
AU - Ng, Christina Sum Yi
AU - Luk, Martha Sin Ki
AU - So, Georgina Yuen Kiu
AU - Chau, Priscilla Sin Ying
AU - Cheung, Irene Kit Man
AU - Chan, Cecilia Lai Wan
N1 - Publisher Copyright:
© The Author(s) 2025. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
PY - 2025
Y1 - 2025
N2 - Purpose: To evaluate the efficacy of an Integrative Body–Mind–Spirit (IBMS) group intervention in modulating inflammatory cytokine balance and improving clinical outcomes in children with atopic dermatitis. Methods: In a randomized, waitlist-controlled trial conducted in Hong Kong, 141 parent–child dyads were assigned to either the IBMS intervention (n = 71) or a waitlist control (n = 70). The IBMS intervention consisted of 6 weekly 3-hour group sessions. Outcomes included inflammatory cytokine levels, eczema severity, physical and emotional impact, and quality of life, assessed at baseline and post-intervention. Results: The IBMS group showed significant reductions in eczema severity and improvements in physical and emotional well-being and quality of life. Significant decreases in cytokine levels were also observed, indicating a shift toward immune balance. Discussion: The IBMS psychosocial intervention demonstrated immunological and clinical benefits, underscoring its potential as a non-pharmacological approach for pediatric eczema.
AB - Purpose: To evaluate the efficacy of an Integrative Body–Mind–Spirit (IBMS) group intervention in modulating inflammatory cytokine balance and improving clinical outcomes in children with atopic dermatitis. Methods: In a randomized, waitlist-controlled trial conducted in Hong Kong, 141 parent–child dyads were assigned to either the IBMS intervention (n = 71) or a waitlist control (n = 70). The IBMS intervention consisted of 6 weekly 3-hour group sessions. Outcomes included inflammatory cytokine levels, eczema severity, physical and emotional impact, and quality of life, assessed at baseline and post-intervention. Results: The IBMS group showed significant reductions in eczema severity and improvements in physical and emotional well-being and quality of life. Significant decreases in cytokine levels were also observed, indicating a shift toward immune balance. Discussion: The IBMS psychosocial intervention demonstrated immunological and clinical benefits, underscoring its potential as a non-pharmacological approach for pediatric eczema.
KW - Integrative Body–Mind–Spirit Model
KW - atopic dermatitis
KW - inflammatory cytokines
KW - non-pharmaceutical intervention
KW - quality of life
UR - https://www.scopus.com/pages/publications/105025239965
UR - https://www.mendeley.com/catalogue/8b741f2b-edf7-3162-9fe9-f38a306cbca1/
U2 - 10.1177/10497315251396784
DO - 10.1177/10497315251396784
M3 - Article
AN - SCOPUS:105025239965
SN - 1049-7315
JO - Research on Social Work Practice
JF - Research on Social Work Practice
ER -